Determinants of Severe Late Ovarian Hyperstimulation Syndrome in Fresh Embryo Transfer Cycles Based on Integration of Decision Tree Classification and Conditional Logistic Regression
نویسندگان
چکیده
Background: To explore possible predictors of severe late ovarian hyperstimulation syndrome (SL-OHSS) in fresh embryo transfer cycles. Methods: We conducted a historical cohort study Chinese tertiary hospital from January 2017 to December 2019, with total 6931 women who had the first included. SL-OHSS was defined as symptoms OHSS occurring 12–17 days after ovulation triggering. Possible determinants occurrence were identified by detection decision tree, effects which estimated conditional logistic regression and restricted cubic spline. Results: Elevated estradiol (E2) on day triggering elevated Anti-Mullerian hormone (AMH) associated an increased risk (p < 0.001). Women E2 trigger ≥3320.2 pg/mL (odds ratio (OR): 2.20; 95% confidence interval (CI): 1.03–4.68), or <3320.2 AMH ≥4.62 ng/mL (OR: 5.44; CI: 2.29–12.90), compared their counterparts. >3320.2 >4.62 highest 13.20; 3.87–45.02) when ≤3320.2 ≤4.62 ng/mL. This association not linear. Conclusions: Serum concentration levels at baseline may predict These biomarkers be valuable determining optimum strategy limit SL-OHSS.
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ژورنال
عنوان ژورنال: Clinical and Experimental Obstetrics & Gynecology
سال: 2023
ISSN: ['0390-6663', '2709-0094']
DOI: https://doi.org/10.31083/j.ceog5002036